Dr. Zack Smith

Dr. William Zachary Smith, MD, DABA is the Founder and CEO of The PainSmith and is one of the best pain management doctors in San Antonio. He is dual board certified in Anesthesiology and Pain Medicine by the American Board of Anesthesiology.

He received his undergraduate degree from the University of Texas at Austin in Electrical Engineering, during which time he worked for the United States Navy as a civilian doing sonar research. He worked at an engineering firm in Houston for several years, but after experiencing the healthcare system first-hand, he decided to switch careers and become a physician.

He completed his M.D. with Distinction in Research at the University of Texas Health Science Center San Antonio, TX. He then completed an Internship in Neurosurgery, a Residency in Anesthesiology and a Fellowship in Pain Medicine at the University of Nebraska Medical Center in Omaha, NE. While in residency/fellowship, Dr. Smith was part of a study that performed interventional pain procedures as salvage therapy for critically ill Covid-19 patients.

Dr. Smith originally became interested in spine, neck, and nerve pain in college when his mother developed significant neck and arm pain. She first tried typical conservative treatments, including physical therapy, chiropractic care, and oral medications. Ultimately, she underwent several surgeries and unfortunately developed complex regional pain syndrome that continues to affect her daily quality of life decades later.

“I was able to witness first hand how untreated pain syndromes can influence quality of life, and this helped to inspire me to become an interventional pain physician.”

When not working on the forefront of treating chronic pain, Dr. Smith resides in nearby New Braunfels with his wife, Leslie, and their soon-to-be first born. He enjoys homebrewing his own beer, is an avid board game player, and loves to hike and kayak at the beautiful Canyon Lake.

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Call: (210) 963-7493 | 731 Carnoustie Drive, Suite 102, San Antonio, TX

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08/03/2026

Dear Painsmith Patients,

It has been a pleasure caring for all of my patients over the past several years here in San Antonio. Unfortunately, due to ongoing personal health issues, I will be unable to continue caring for you with the same high level of care you are used to. Because of this, my last date treating patients at Painsmith will be September 5, 2026.

If you have a scheduled appointment prior to this date, we are more than happy to keep that appointment, and will attempt to accommodate other patients who wish to be seen prior to our final date. If you wish to cancel your appointment please contact the office.

Your medical records will remain at Painsmith, and we are happy to forward your records to yourself or a physician of your choosing. Our office staff can assist you with forwarding or obtaining your records. Additionally, we are currently in discussions with other local area pain physicians who have expressed interest in assisting with your care moving forward. If we locate a physician with both capacity and capability to deliver the same quality of care, we will provide an update at that time.

Thank you,

William (Zack) Smith, MD